Immediate Extinction Versus Delayed Extinction
Maren, S. (2014). Nature and causes of the immediate extinction deficit: A brief review. Neurobiology of Learning and Memory, 113(Supplement C), 19-24. doi: 10.1016/j.nlm.2013.10.012
Last week, one of my colleagues raised a question that I didn't aware before: the immediate extinction and delayed extinction may be different substantially. This difference is so huge that, as she said, replicate a delayed extinction paradigm with an immediate extinction one may be of great danger. So I checked the literature, and do found many studies did the comparison. In the article review part, the author mentioned 17 article, including 4 studies using human subjects and 13 studies used animals (mostly rats).
Although the initial reports about the immediate extinction are very positive ( immediate extinction could "erase" fear memory) (Meyers, et al., 2006), but later studies found complicated results. There are more studies reported the immediate extinction deficit, i.e., immediate extinction after fear condition cannot lead to extinction (more spontaneous recovery, more freezings, easier to reinstatement)
In this case, I guess we should be very cautious using immediate extinction paradigm to replicate a delayed extinction experiment.
Last week, one of my colleagues raised a question that I didn't aware before: the immediate extinction and delayed extinction may be different substantially. This difference is so huge that, as she said, replicate a delayed extinction paradigm with an immediate extinction one may be of great danger. So I checked the literature, and do found many studies did the comparison. In the article review part, the author mentioned 17 article, including 4 studies using human subjects and 13 studies used animals (mostly rats).
Although the initial reports about the immediate extinction are very positive ( immediate extinction could "erase" fear memory) (Meyers, et al., 2006), but later studies found complicated results. There are more studies reported the immediate extinction deficit, i.e., immediate extinction after fear condition cannot lead to extinction (more spontaneous recovery, more freezings, easier to reinstatement)
In this case, I guess we should be very cautious using immediate extinction paradigm to replicate a delayed extinction experiment.
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