Noradrenergic modulation on stress-evoked salience network activity
Hermans, E. J., van Marle, H. J. F., Ossewaarde, L., Henckens, M. J. A. G., Qin, S., van Kesteren, M. T. R., . . . Fernández, G. (2011). Stress-Related Noradrenergic Activity Prompts Large-Scale Neural Network Reconfiguration. Science, 334(6059), 1151-1153. doi:10.1126/science.1209603 After re-read this paper I think I get more information from it. This study included two experiments, one regular fMRI study, one with Neuro-pharmaceutical manipulations. In the first experiment, participants viewed highly stressful video clips with self-referential instruction while their brain was scanned. Using model free data-analysis (i.e., multi-voxel), the authors found that the sensory network (visual cortex) are highly correlated among participants in both aversive and neutral conditions. However, brain regions previous claimed to be involved in the intrinsic connectivity network (ICN, include autonomic neuroendocrine control [frontoinsular cortex, dorsal anterior cingulate corte...